At this time, I would highly recommend you consider planning your trip by first making a list of the museums you want to absolutely visit. If both Accademia and Uffizi are on that list, I suggest you book those museums directly. Those are the ones with long lines that have number of visitors limited down from what they were before, so it makes sense to book those, even in October.
Which other museums are on your list? It is likely you don't have to buy tickets ahead for those, considering you're coming in October.
The numbers of tourists in the city are still small compared to the past, and I doubt they will be the same as in the past by then. Starting in 2 days, across Italy all museums will require the Green Pass or its equivalent in order for anyone to visit. This as Covid cases have seen an increase over the last few weeks. If the measures planned for limiting activities for those with Green Passes works, we hope everything will still be open in October. The Firenze Card has not been reactivated because not all museums are yet back open with regular hours.... so they don't want to offer something you might not be able to fully use. If things were to go well and museums reopen, then the card might be reactivated before your arrival and you can just buy it once you arrive. However, I'd recommend that if you want to wait and see, that by the second half of September you check back here with us. We will let you know how things are - and if by then you haven't booked tickets for the Uffizi and Accademia, to go ahead and book.